Detpool

Abilities: Exceptional regeneration. This is perhaps his greatest strength. Deadpool can survive virtually any injury, from a severed limb to more serious damage. Recovery time depends on the severity of the injury: from a few seconds to several minutes. Furthermore, this ability allows him to overload his muscles and temporarily achieve superhuman levels of strength.
Immune to disease and toxins. His healing factor protects him from all known diseases and poisons—he simply cannot become ill or die from a toxin.
Telepathy Immunity. Due to this same healing factor, Deadpool is immune to telepathic attacks, including mind reading.
Superhuman reflexes, strength, endurance, and agility. He is at the peak of his physical abilities, which, combined with his martial arts skills, makes him extremely dangerous in close combat.
Combat Mastery. Deadpool is a skilled swordsman (often wielding two katanas), a master of hand-to-hand combat, and an accomplished marksman. Breaking the fourth wall. This isn't exactly a superpower in the classic sense, but it's a very distinctive trait: Deadpool is aware that he exists in a comic/film and actively interacts with the reader/viewer. Sometimes, this allows him to literally change the course of events or obtain information from the "outside world."
Technopathy. In some storylines (such as when he was Weapon XI), he was given the ability to control electrical and wireless devices, as well as receive electrical signals.
Adapting other people's abilities. In certain stories, Stryker combined the DNA of various mutants (Cyclops, John Wraith, Chris Bradley) into one body so that Deadpool could harness their powers—for example, firing optic blasts, teleporting, or manipulating technology.
Adamantium Skeleton. In one iteration (including the films), Stryker implanted Wade with an adamantium-bonded skeleton—like Wolverine's.