Pinky and the Brain

Pinky and the Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is highly intelligent, self-centered and scheming, while Pinky is good-natured but feeble-minded.
Pinky is a genetically modified mouse who shares the same cage as Brain at Acme Labs. Pinky is an extremely unstable and hyperactive mouse. He has several verbal tics, such as "Narf", "Zort", "Poit", and "Troz", the last of which he started saying after noticing it was "Zort" reflected backwards in a mirror. Pinky's appearance contrasts with Brain's — while Brain is short, has a crooked tail and pink sclerae, and speaks in a deeper, more eloquent manner, Pinky has a straight tail, blue sclerae, and a severe overbite, is taller than Brain and speaks in a high-pitched voice with a Cockney British accent. Pinky's name was inadvertently given to him by Brain himself: when insulting the two scientists responsible for their gene splicing while talking to himself, Brain claimed the scientists had "less knowledge in both their heads than I do in my...pinky!" Pinky then responded with "Yes?", believing that Brain was referring to him.
Pinky is more open-minded, kinder, and generally happier than Brain. Troubles never ruin his day, possibly because he is too scatter-brained to notice them. He steadfastly helps Brain toward world domination, even though Brain usually berates, belittles and even abuses him. Pinky actually seems to enjoy this, often laughing after he is hit on the head. He is obsessed with trivia, spending a lot of time watching television in the lab and following popular culture fads. Sometimes, Pinky even finds non-rational solutions to problems. Pinky often points out flaws in the Brain's plans, which the Brain consistently ignores. The issues Pinky brings up can ironically lead to the downfall of the plan in the given night's plot. He is also Brain's moral compass and his only true friend.

The Brain or "Brain" for short looks and sounds like Orson Welles. Brain's name is the backronym for the eponymous project: "Biological Recombinant Algorithmic Intelligence Nexus". His tail is angular and bent — he often uses it to pick the lock of the cage door — and his head is large and wide, housing his abnormally large brain. He is highly intelligent and develops complex plans for global domination using politics, cultural references, and his own inventions toward his goal. He seems coldly unemotional, speaking in a snarky deadpan voice. Nevertheless, Brain has a subtle sense of humor and has even fallen in love, with Trudie. Due to his stature and megalomania, Brain has been compared to Don Quixote and has been called a pop culture depiction of Napoleon Bonaparte. Brain sees his inevitable rise to power as good for the world and not as mere megalomania. Brain wants to take over the world not for the sake of being a dictator, like his rival Snowball, but because he believes that he could do a much better job of it than the people currently in charge. Brain has even helped save the world by doing everything in his power to prevent Snowball's evil schemes, knowing that a world under Snowball's rule would be a worst-case scenario.